CB Insights took at look at which seed deals received follow-on funding and listed investors by the ability of their portfolios to raise new money. Here are the top 10.

Angel investors continued to pay up for deals in 2012, though the median round size slipped slightly for the year, according to the Halo Report of angel group investment trends.

Investment activity rose modestly to $6.9 billion in the quarter (vs. $6.8 billion in the fourth quarter) and deal volume climbed to 841, according to a study from CB Insights.

Venture investors seem to have come to terms with the notion that a 1,000 or so seed companies may find their road comes to an end from the so-called Series A crunch. The next question is exactly which companies are most likely to run out of gas?

Big data means big business for venture investors. Venture capital going to startups with big-data-related business plans came close to $1.4 billion last year and accounted for more than 5% of all venture dollars placed with young companies.

During the year, 2,277 private tech companies were acquired globally, according to a study from CB Insights. While most of the deals were relatively small, or completed without a disclosed transaction value, eight of the companies were purchased for more than $1 billion.

Venture investors pulled back during the fourth quarter with dollars going to startups falling 9% and seed investors becoming more cautious. The quarter saw renewed interest in health care investing and a dip in funding for Internet startups.

Angels continued to aggressively put money to work in the third quarter of last year, with medianl round size jumping to a 15-month high and dollars going to mobile startups rising to 16.5% of total investments.

The Series A crunch boils down to this: Too many seed fundings, too few follow-on A financings. In other words, excessive supply and limited demand. So if you want to get your arms around the expected funding shortfall, do the math. That’s what CB Insights did in a recent study.

Call them the cream of the venture crop, the 472 high flying U.S.-based companies with valuations above $100 million and exciting businesses to justify them.