Just two days after its most recent and biggest fundraising, VC-backed pharmaceutical company Chimerix Inc. has locked in millions more in the form of a federal contract. The Biomedical Advanced Research & Development Authority (BARDA) has committed funding of $24.8 million to a medical treatment of smallpox, which could grow to more than $80 million [...]

Chimerix, the North Carolina-based antiviral drug maker, secured a Series F funding for about $45 million, peHUB has learned from multiple sources. Management and directors at the company met today at the company’s headquarters and the fundraise is expected to be announced next week. Several of Chimerix’s prior investors joined in the latest funding round, [...]

Publicly traded data warehousing company Teradata will pay $525 million to buy venture-backed Aprimo, a cloud-based marketing software company. Indianapolis, Indiana-based Aprimo has raised venture financing from firms including Frazier Technology Ventures, Blue Chip Venture Company and Sigma Partners.

Seattle-based DocuSign has raised $27 million in Series C financing. The round was led by Scale Venture Partners, and include participation from existing shareholders Sigma Partners, Ignition Partners, Frazier Technology Ventures and Salesforce.com. DocuSign provides electronic signature technology for individuals and businesses. The company will use the latest round for growth and to launch new cloud-based technology and services in 2011.

Possibly over 50, according to the National Venture Capital Association — and that doesn’t include firms that have not renewed their memberships in the trade association for next year.

The NVCA won’t name names, but reports that its membership has fallen from 480 firms in 2007 (an all-time high) to 450 firms in 2008 to 425 firms in 2009 — a decrease of 55 firms, over 11%.

Most of the firms dropping out did so because they’re not raising a new fund, said NVCA vice president Emily Mendell.

Frazier Technology Ventures yesterday said that it would no longer make new investments, nor raise another fund. As part of that announcement, general partner Len Jordan said that he would be joining fellow Seattle-based venture firm Madrona. So we’ve got 5 Questions for Len:

1. When did you guys formally decide that Fund III just wasn’t going to happen?

Earlier, in the first half of this year. The fund-raising environment was just very difficult, and I don’t think we foresaw it getting much better anytime soon. We’re a relatively new group, so we drew the conclusion that we should suspend.

I want to emphasize, though, that it had nothing to do with our portfolio, which we feel very good about. I think we have a lot of value inside our 11 active portfolio companies, and had a very good exit last year when SNAPin was acquired by Nuance.

Some big news from the Emerald City was posted just a few minutes ago.

TechFlash is reporting that Frazier Technology Ventures has agreed to dissolve. The firm will not make any new investments as it winds down its current portfolio. (Update: A Madrona rep writes in to say that FTV will continue to manage its existing investments, rather than “dissolve” the firm)

The Seattle-based early stage tech investor, affiliated with Frazier Healthcare Ventures, raised $104 million for its second fund in 2004 from LPs like the Wisconsin State Investment Board, and was reportedly trying to raise a successor fund vehicle earlier this year.